Medical Journal

Impact of change in iron status over time on clinical outcomes in heart failure according to ejection fraction phenotype.
Sarah Fitzsimons, Tee Joo Yeo , Lieng H Ling , David Sim , Kui Toh Gerard Leong , Poh Shuan Daniel Yeo , Hean Yee Ong , Fazlur Jaufeerally , Tze P Ng , Katrina Poppe, Mayanna Lund , Gerry Devlin, Richard Troughton, Carolyn S P Lam, A Mark Richards, Robert N Doughty.

ESC Heart Fail. 2021 Sep 30.
https://pubmed.ncbi.nlm.nih.gov/34592056/

Atrial Fibrillation and the Prognostic Performance of Biomarkers in Heart Failure.
Tan ESJ, Chan SP, Liew OW, Chong JPC, Leong GKT, Yeo DPS, Ong HY, Jaufeerally F, Yap J, Sim D, Ng TP, Ling LH, Lam CSP, Richards AM.

Clin Chem. 2021 Jan 8;67(1):216-226.
https://pubmed.ncbi.nlm.nih.gov/33279970/

Ethnic differences in quality of life and its association with survival in patients with heart failure.
Stein G, Teng TK, Tay WT, Richards AM, Doughty R, Dong Y, Sim D, Yeo PSD, Jaufeerally F, Leong G, Soon D, Ling LH, Lam CSP.

Clin Cardiol. 2020 Sep;43(9):976-985.
https://pubmed.ncbi.nlm.nih.gov/32562317/

Effectiveness of telemonitoring-enhanced support over structured telephone support in reducing heart failure-related healthcare utilization in a multi-ethnic Asian setting.
Leng Chow W, Aung CYK, Tong SC, Goh GS, Lee S, MacDonald MR, Ng AN, Cao Y, Ahmad AE, Yap MF, Leong G, Bruege A, Tesanovic A, Riistama J, Pang SY, Erazo F.J

Telemed Telecare. 2020 Jul;26(6):332-340.
https://pubmed.ncbi.nlm.nih.gov/30782070/

N-terminal pro-B-type natriuretic peptide and prognosis in Caucasian vs. Asian patients with heart failure.
Tromp J, Richards AM, Tay WT, Teng TK, Yeo PSD, Sim D, Jaufeerally F, Leong G, Ong HY, Ling LH, van Veldhuisen DJ, Jaarsma T, Voors AA, van der Meer P, de Boer RA, Lam CSP. ESC Heart Fail.

2018 Apr;5(2):279-287.
https://www.ncbi.nlm.nih.gov/pubmed/29380931

Mortality associated with heart failure with preserved vs. reduced ejection fraction in a prospective international multi-ethnic cohort study.
Lam CSP, Gamble GD, Ling LH, Sim D, Leong KTG, Yeo PSD, Ong HY, Jaufeerally F, Ng TP, Cameron VA, Poppe K, Lund M, Devlin G, Troughton R, Richards AM, Doughty RN. Eur Heart J.

2018 May 21;39(20):1770-1780. 
https://www.ncbi.nlm.nih.gov/pubmed/29390051

Cost-effectiveness of sacubitril/valsartan versus enalapril in patients with heart failure and reduced ejection fraction.
Liang L, Bin-Chia Wu D, Aziz MIA, Wong R, Sim D, Leong KTG, Wei YQ, Tan D, Ng K. J Med Econ.

2018 Feb; 21(2):174-181. 
https://www.ncbi.nlm.nih.gov/pubmed/28959905

Risk stratification of Asian patients with heart failure and reduced ejection fraction: the effectiveness of the Echo Heart Failure Score.
Bosch L, Carluccio E, Coiro S, Gong L, Sim D, Yeo D, Jaufeerally F, Leong KTG, Ong HY, Pin NT, Richards AM, Arslan F, Ling LH, Lam CSP, Ambrosio G. Eur J Heart Fail.

2017 Dec;19(12):1732-1735. 
https://www.ncbi.nlm.nih.gov/pubmed/28884497

N-terminal pro-B-type natriuretic peptide and prognosis in Caucasian vs. Asian patients with heart failure.
Tromp J, Richards AM, Tay WT, Teng TK, Yeo PSD, Sim D, Jaufeerally F, Leong G, Ong HY, Ling LH, van Veldhuisen DJ, Jaarsma T, Voors AA, van der Meer P, de Boer RA, Lam CSP.

ESC Heart Fail. 2018 Apr;5(2):279-287. 
https://www.ncbi.nlm.nih.gov/pubmed/29380931

The prognostic value of highly sensitive cardiac troponin assays for adverse events in men and women with stable heart failure and a preserved vs. reduced ejection fraction.
Gohar A, Chong JPC, Liew OW, den Ruijter H, de Kleijn DPV, Sim D, Yeo DPS, Ong HY, Jaufeerally F, Leong GKT, Ling LH, Lam CSP, Richards AM. Eur J Heart Fail.

2017 Dec; 19(12):1638-1647. 
https://www.ncbi.nlm.nih.gov/pubmed/28849609

Prevalence and Clinical Significance of Diabetes in Asian Versus White Patients With Heart Failure.
Bank IEM, Gijsberts CM, Teng TK, Benson L, Sim D, Yeo PSD, Ong HY, Jaufeerally F, Leong GKT, Ling LH, Richards AM, de Kleijn DPV, Dahlström U, Lund LH, Lam CSP.

JACC Heart Fail. 2017 Jan;5(1):14-24.
https://www.ncbi.nlm.nih.gov/pubmed/28447583

Right ventricular dysfunction in left-sided heart failure with preserved versus reduced ejection fraction. 
Bosch L, Lam CSP, Gong L, Chan SP, Sim D, Yeo D, Jaufeerally F, Leong KTG, Ong HY, Ng TP, Richards AM, Arslan F, Ling LH. Eur J Heart Fail.

2017 Dec;19(12):1664-1671.
https://www.ncbi.nlm.nih.gov/pubmed/28597497

Thymosin beta-4 is elevated in women with heart failure with preserved ejection fraction.
Chester, Lee Drum, Warren, Kok Yong Tan, Siew-Pang Chan, Leroy, Sivappiragasam Pakkiri, Jenny P.C. Chong, OI WAH LIEW, TZE PIN NG, Lieng, H. Ling, David Sim, Kui Toh, Gerard Leong, POH SHUAN DANIEL YEO, HEAN YEE ONG, Fazlur Jaufeerally, Raymond, Ching Chiew Wong, PING CHAI, Adrian, F Low, Pia Davidsson, Mathias Liljeblad, Ann-Sofi, Nancy Söderling, Li-Ming Gan, Ratan, V Bhat, Kristy Purnamawati, Carolyn, SP Lam, A M Richards. J Am Heart Assoc.

2017 Jun 13;6(6).
https://www.ncbi.nlm.nih.gov/pubmed/28611096 

Prognostic Factors After Index Hospitalization for Heart Failure With Preserved Ejection Fraction.
Weiting Huang, Siang Chew Chai, Shao Guang Sheldon Lee, Michael R. MacDonald, Kui Toh Gerard LeongAm J Cardiol. 

2017 Jun 15;119(12):2017-2020,
https://www.ncbi.nlm.nih.gov/pubmed/28477861

Risk Stratification Model for 30-Day Heart Failure Readmission in a Multiethnic South East Asian Community. 
Leong KT, Wong LY, Aung KC, Macdonald M, Cao Y, Lee S, Chow WL, Doddamani S, Richards AM. Am J Cardiol.

2017 May 1;119(9):1428-1432.
https://www.ncbi.nlm.nih.gov/pubmed/28302271

Comparison of Characteristics and Outcomes of Heart Failure Patients with Preserved Versus Reduced Ejection Fraction a Multi-Ethnic South East Asian Cohort.
Michael R MacDonald, Sheldon Lee, Pangping Wee, Khim Leng Tong, Kui Toh Gerard Leong. Am J Cardiol. 

2016 Oct 15;118(8):1233-1238
https://www.ajconline.org/article/S0002-9149(16)31248-6/fulltext?rss=yes&code=ajc-site

Ethnic Differences In The Association Of QRS-duration With Ejection Fraction And Outcome In Heart Failure.
Crystel M. Gijsberts, Lina Benson, Ulf Dahlström, David Sim, P.S. Daniel Yeo, Hean Yee Ong, Fazlur Jaufeerally, Gerard K.T. Leong, Lieng H. Ling, A. Mark Richards, Dominique P.V. de Kleijn, Lars H. Lund, Carolyn S.P. Lam.

Heart. 2016;102:1464-1471. 
https://heart.bmj.com/content/102/18/1464

Growth differentiation factor 15 in heart failure with preserved vs. reduced ejection fraction.
Chan MM, Santhanakrishnan R, Chong JP, Chen Z, Tai BC, Liew OW, Ng TP, Ling LH, Sim D, Leong KT, Yeo PS, Ong HY, Jaufeerally F, Wong RC, Chai P, Low AF, Richards AM, Lam CS

Eur J Heart Fail. 2016 Jan;18(1):81-8. 
https://www.ncbi.nlm.nih.gov/pubmed/26497848

Circulating microRNAs in heart failure with reduced and preserved left ventricular ejection fraction.
Wong LL, Armugam A, Sepramaniam S, Karolina DS, Lim KY, Lim JY, Chong JP, Ng JY, Chen YT, Chan MM, Chen Z, Yeo PS, Ng TP, Ling LH, Sim D, Leong KT, Ong HY, Jaufeerally F, Wong R, Chai P, Low AF, Lam CS, Jeyaseelan K, Richards AM.

Eur J Heart Fail. 2015 Apr; 17 (4):393-404. 
https://www.ncbi.nlm.nih.gov/pubmed/25619197

A tale of two tachycardias.
Yeo C, Chow J, Leong KT, Ho KL. 

Singapore Med J2015 Jan; 56(1):e10-3. 
https://www.ncbi.nlm.nih.gov/pubmed/25640105

Impact Of Sex On Clinical Characteristics And In-Hospital Outcomes In A Multi-Ethnic Southeast Asian Population Of Patients Hospitalized For Acute Heart Failure.
Lam CS, Chang P, Chia SY, Sim LL, Gao F, Lee FL, Chai P, Wong RC, Seow SC, Leong GK, Yeo PS, Sim D, Chua T, Kwok BW.

ASEAN Heart J. 2014;22(1). 
https://www.ncbi.nlm.nih.gov/pubmed/26316666

Iron deficiency in a multi-ethnic Asian population with and without heart failure: prevalence, clinical correlates, functional significance and prognosis.
Tee Joo Yeo, Poh Shuan Daniel Yeo, Raymond Ching-Chiew Wong, Hean Yee Ong, Kui Toh Gerard Leong, Fazlur Jaufeerally, David Sim, Rajalakshmi Santhanakrishnan, Shir Lynn Lim, Michelle M.Y. Chan, Ping Chai, Adrian F. Low, Lieng H. Ling, Tze Pin Ng, A. Mark Richards, and Carolyn S.P. Lam. 

European Journal of Heart Failure. Eur J Heart Fail. 2014 Oct; 16 (10):1125-32. 
https://www.ncbi.nlm.nih.gov/pubmed/25208495

Renal Sympathetic Denervation for the Treatment of Refractory Hypertension.
Kui Toh Gerard Leong, Antony Walton, Henry Krum.

Annual Review of Medicine. Vol. 65:349-365. January 2014. 
https://www.annualreviews.org/doi/abs/10.1146/annurev-med-051812-145353

How Does Renal Denervation Lower Blood Pressure and When Should This Technique Be Considered for the Treatment of Hypertension? 
Kui Toh Gerard Leong, Henry Krum.

Current Cardiology ReportsSeptember 2013, 15:414
https://www.ncbi.nlm.nih.gov/pubmed/24057895

The Singapore Heart Failure Outcomes and Phenotypes (SHOP) Study and Prospective Evaluation of Outcome in Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PEOPLE) Study: Rationale and Design.
Santhanakrishnan R, Ng TP, Cameron VA, Gamble GD, Ling LH, Sim DLeong GK, Yeo PS, Ong HY, Jaufeerally F, Wong RC, Chai P, Low AF, Lund M, Devlin G, Troughton R, Richards AM, Doughty RN, Lam CS. 

Journal of Cardiac Failure. J Card Fail. 2013 Mar;19(3):156-62
https://www.ncbi.nlm.nih.gov/pubmed/23482075

Growth Differentiation Factor 15, ST2, high sensitivity Troponin T and N-terminal pro-B-type Natriuretic Peptide in Heart Failure with Preserved versus Reduced Ejection Fraction.
Rajalakshmi Santhanakrishnan, Jenny PC Chong, Tze P Ng, Lieng H Ling, David Sim Kui Toh G Leong, Daniel Yeo Hean Y Ong, Fazlur Jaufeerally, Raymond Wong, Chai Ping, Adrian F Low Arthur Mark Richards, Carolyn SP Lam. 

Eur J Heart Fail2012 Dec;14 (12):138-47. 
https://www.ncbi.nlm.nih.gov/pubmed/22869458

Heart failure in Asia: the present reality and future challenges. Invited review article. S. Lee, R. Khurana, and K.T.G. Leong.
European Heart Journal Supplements. 

European Heart Journal Supplements (2012) 14 (Supplement A), A51–A52.

Precipitant in Acute Heart Failure in a Multi-ethnic Asian Urban Cohort Study.
Kui Toh Gerard Leong, Cao Yan, Ping Ping Goh. 

Heart Asia. 2011; 3:66-70. 
https://www.ncbi.nlm.nih.gov/pubmed/27325996

Heart Failure Cohort in Singapore with Defined Criteria: Clinical Characteristics and Prognosis in a Multi-ethnic Hospital Based Cohort in Singapore. 
Leong KT, Goh PP, Chang BC, Lingamanaicker J. 

Singapore Med J2007 May; 48(5): 408-14.
https://www.ncbi.nlm.nih.gov/pubmed/17453098

(This study received the First prize, Singapore Medical Journal Best research paper award 2007).

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